Interdisciplinarity is seen as a desirable aspect of research projects that is often promoted by research institutions. However, our study reveals that interdisciplinary research projects are associated with lower citation counts and worse journal placements. These findings show that there is a misalignment between the goals of research institutions and researchers, because researchers need highly ranked publications for their promotions. We study a sample of over 13,000 research articles published in economics journals in 2011 and 2012 and present three novel measures of interdisciplinarity. We conduct a Specification Curve (SC) Analysis, which allows for a transparent discussion of data analytic decisions and the visualization of their impact on effect sizes. Furthermore, we find that conducting interdisciplinary research is not a high-risk, high-reward endeavor but instead: that citation counts to interdisciplinary articles do not catch up with those of non-interdisciplinary articles over time. Our results are not due to a false classification of cross disciplinary articles as having low interdisciplinarity, as shown by a robustness exercise where we include business articles and we show that effect sizes are more emphasized for high-ability researchers. The results of this study may be used to better align researcher and institutional goals.